Chain Assault — Rune Effect

Effect

Damaging an enemy champion with an active ability marks them. Your next 2 attacks or abilities deal 20 - 35 (+5% bonus AD, +2.5% AP) bonus adaptive damage. Cooldown: 15s.

Champions who run Chain Assault

None of the 238 captured builds included this rune.

47% of rune slots could not be read, so more champions run this rune than the table shows.

In our recommended runes

None of our recommended rune pages include this rune.

Other runes in Domination

• Cheap Shot
• Empowered Attack
• Eyeball Collector
• Hubris
• Ingenious Hunter
• Relentless Hunter
• Sudden Impact
• Tyrant
• Zombie Ward

About the data on this page

Effect text is as written in game. Pick counts and win rates were read from the in-game loadout screen’s "Popular" tab, captured between 2026-08-26 and 2026-08-29. The recommended runes are written by us.